โ† ingredient library
AntimicrobialKeratolyticSebum Regulator

Benzoyl Peroxide

๐Ÿ† hero ingredient Tier 1 Evidence

what it does

A topical antibacterial that kills acne-causing P. acnes bacteria through oxidative activity while providing mild exfoliation. Available OTC in concentrations from 2.5โ€“10%.

dermai take

Straight-up nukes acne bacteria with oxygen โ€” brutal, effective, no notes. 2.5% works as well as 10% with way less irritation, so don't be a hero. Will bleach your towels. You have been warned.

targets these concerns

don't combine with

Benzoyl peroxide oxidises tretinoin on contact, rendering it inactive. Never layer them in the same session.

๐Ÿ’ก AM: benzoyl peroxide. PM: tretinoin only, after it fully absorbs.

Benzoyl peroxide degrades retinol through oxidation, completely eliminating its anti-ageing efficacy.

๐Ÿ’ก Use in strictly separate AM/PM sessions โ€” never in the same layer.

Vitamin Cmedium

Benzoyl peroxide can oxidise ascorbic acid, reducing vitamin C's brightening and antioxidant effect.

๐Ÿ’ก AM: vitamin C. PM or separate session: benzoyl peroxide.

the studies

"Intense pulsed light versus benzoyl peroxide."
Journal of population therapeutics and clinical pharmacology (2022) ยท Al Abdullah MJ, Mahdi YG

products with this ingredient

Persol-AC 2.5% GelGalderma