EmollientOcclusiveAntioxidant

Squalane

✅ solid choice Tier 2 Evidence

what it does

A saturated, stable version of squalene derived from olives or sugarcane that closely mimics the skin's own sebum. Non-comedogenic emollient that seals in moisture without clogging pores.

dermai take

The cheat-code emollient. Squalane is basically your own skin oil but better — stable, non-comedogenic, non-greasy. Works on literally every skin type including acne-prone. One of those 'should be in every routine' ingredients.

targets these concerns

Dryness Eczema-prone

the studies

"Clinical evaluation of fullerene-C60 dissolved in squalane for anti-wrinkle cosmetics."

Journal of nanoscience and nanotechnology (2010) · Kato S, Taira H, Aoshima H et al.

"High-dose squalene ingestion increases type I procollagen and decreases ultraviolet-induced DNA damage in human skin in vivo."

Clinical and experimental dermatology (2009) · Cho S, Choi CW, Lee DH et al.