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Humectant

Hyaluronic Acid

🏆 hero ingredient Tier 1 Evidence

what it does

A naturally occurring polysaccharide that holds up to 1000x its weight in water, making it the most studied humectant in skincare. Naturally found in skin, levels decrease with age.

dermai take

The hydration hype is actually real — this stuff holds 1000x its weight in water. Apply it on damp skin or it'll pull moisture OUT of you in dry climates. Boring name, genuinely impressive science.

targets these concerns

Fine LinesDrynessSensitivityEczema-prone

the studies

"The Effects of Dietary Supplementation with Collagen and Vitamin C and Their Combination with Hyaluronic Acid on Skin Density, Texture and Other Parameters: A Randomised, Double-Blind, Placebo-Controlled Trial."
Nutrients (2024) · Žmitek K, Žmitek J, Hristov H et al.
"Comparison of the effects of polynucleotide and hyaluronic acid fillers on periocular rejuvenation: a randomized, double-blind, split-face trial."
The Journal of dermatological treatment (2022) · Lee YJ, Kim HT, Lee YJ et al.
"A hyaluronic acid-based micro-filler improves superficial wrinkles and skin quality: a randomized prospective controlled multicenter study."
The Journal of dermatological treatment (2023) · Fanian F, Deutsch JJ, Bousquet MT et al.

products with this ingredient

Hydra4B Sunscreen Gel SPF 50Brinton